Mutation Information
Mutation Site
|
V47I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Literature Information
PubMed PMID
|
25362963
|
Published Year
|
2014 |
Journal
|
Scientific reports |
Title
|
Revealing origin of decrease in potency of darunavir and amprenavir against HIV-2 relative to HIV-1 protease by molecular dynamics simulations. |
Author
|
Chen J,Liang Z,Wang W,Yi C,Zhang S,Zhang Q |
Evidence
|
The reason led to this result may be the conformation change induced by the mutation V47I in PR2.
|
|
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