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Mutation Information
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Mutation Site
|
V46I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gag |
|
Viral Reference
|
K03455.1
|
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
30201008
|
|
Clinical information
|
Yes
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Retrovirology |
|
Title
|
Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control. |
|
Author
|
Caetano DG,Côrtes FH,Bello G,Teixeira SLM,Hoagland B,Grinsztejn B,Veloso VG,Guimarães ML,Morgado MG |
|
Evidence
|
VC16 presented a large number of amino acid changes, mainly in Gag epitopes, with reversion of approximately 30% for I34L, V35I, V46I, V82L, A118P, A119T, G123 K, and S125R mutations and an increase from 20 to 30% for H124S, Q1227H, I138L, A146P, V168T, T242 N and A340G from VE to VL.
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HIV Mutation Detail Information