Mutation Information
Mutation Site
|
V32I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Relevant Drug
|
PIs |
Country
|
USA |
Literature Information
PubMed PMID
|
30148406
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2018 |
Journal
|
AIDS research and human retroviruses |
Title
|
Prevalence of Darunavir Resistance in the United States from 2010 to 2017. |
Author
|
Brown K,Stewart L,Whitcomb JM,Yang D,Nettles RE,Lathouwers E |
Evidence
|
The most common individual darunavir RAMs were L33F (identified in 4.3% of samples in 2010 and 2.4% of samples in 2017;p = .001), I84 V (3.4% and 1.5%, respectively;p = .003), and V32I (2.6% and 1.3%;p = .006);the least common darunavir RAM, L76V, was identified in 0.4% of samples in 2010 and 0.3% of samples in 2017 (p = .083;Fig. 2A).
|
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