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Mutation Information
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Mutation Site
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V31I |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
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Vif |
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Viral Reference
|
K03455.1
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Literature Information
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PubMed PMID
|
31665623
|
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Published Year
|
2019 |
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Journal
|
Cell reports |
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Title
|
HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators. |
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Author
|
Salamango DJ,Ikeda T,Moghadasi SA,Wang J,McCann JL,Serebrenik AA,Ebrahimi D,Jarvis MC,Brown WL,Harris RS |
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Evidence
|
Interestingly, exchanging V31I and G33R in LAI Vif together, but not separately, was sufficient to confer EGFP-PPP2R5A degradation activity (Figure S4B).
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HIV Mutation Detail Information