Mutation Information
Mutation Site
|
V27I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
C |
Country
|
China |
Literature Information
PubMed PMID
|
17900990
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2007 |
Journal
|
Clinical immunology (Orlando, Fla.) |
Title
|
The high prevalence of the I27 mutant HBcAg18-27 epitope in Chinese HBV-infected patients and its cross-reactivity with the V27 prototype epitope. |
Author
|
Liu HG,Chen WW,Fan ZP,Yang HY,Shi M,Zhang Z,Luan SS,Zhang H,Lu P,Tien P,Wang FS |
Evidence
|
Approximately 93.3% (98/105) of the core genes that were sequenced contained mutations with amino acid substitution at position 27 of the core protein: a mutation from a valine to an isoleucine (V27I).
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