Mutation Information
Mutation Site
|
V17F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PreC |
Genotype/Subtype
|
B |
Country
|
Japan |
Literature Information
PubMed PMID
|
19850315
|
Disease
|
Fulminant hepatitis B
|
Published Year
|
2009 |
Journal
|
Virology |
Title
|
Enhanced intracellular retention of a hepatitis B virus strain associated with fulminant hepatitis. |
Author
|
Inoue J,Ueno Y,Nagasaki F,Wakui Y,Kondo Y,Fukushima K,Niitsuma H,Shimosegawa T |
Evidence
|
Focusing on the core promoter and precore regions, an amino acid mutation of residue 17 of Val to Phe (V17F) in the precore region was found besides the precore stop mutation and the double core promoter mutations (corresponding to aa 130 and 131 in the X gene).
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