Mutation Information
Mutation Site
|
V17F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PreC |
Amino acid_Mutation
|
G1862T |
Genotype/Subtype
|
D |
Literature Information
PubMed PMID
|
18201182
|
Published Year
|
2008 |
Journal
|
Hepatology research : the official journal of the Japan Society of Hepatology |
Title
|
A valine to phenylalanine mutation in the precore region of hepatitis B virus causes intracellular retention and impaired secretion of HBe-antigen. |
Author
|
Chen CY,Crowther C,Kew MC,Kramvis A |
Evidence
|
The G1862T mutation in the bulge of the RNA encapsidation signal (codon 17) changes the valine at the −3 position to the signal peptide cleavage site at position 19 to phenylalanine
|
|
|