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Mutation Information
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Mutation Site
|
V179D |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
efavirenz (EFV);etravirine (ETR);nevirapine (NVP);rilpivirine (RPV) |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
32371875
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Scientific reports |
|
Title
|
HIV-1 molecular epidemiology and drug resistance-associated mutations among treatment-naïve blood donors in China. |
|
Author
|
Zhao J,Lv X,Chang L,Ji H,Harris BJ,Zhang L,Jiang X,Guo F,Hackett J Jr,Yin P,Cloherty GA,Rodgers MA,Wang L |
|
Evidence
|
Most of the NNRTI DRMs (V179D/E [72.7%, 16/22]) were observed in HIV-1 infected blood donors and a combination of V179D and K103R were found in two samples may synergistically reduce ARV drug susceptibility.
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HIV Mutation Detail Information