Mutation Information
Mutation Site
|
V168A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
Ba |
Immune Escape
|
Y |
Literature Information
PubMed PMID
|
32978866
|
Disease
|
HBV infection
|
Published Year
|
2021 |
Journal
|
Hepatology research : the official journal of the Japan Society of Hepatology |
Title
|
Case of hepatitis B virus reactivation after ibrutinib therapy in which the patient remained negative for hepatitis B surface antigens throughout the clinical course. |
Author
|
Tsuruya K,Anzai K,Shioyama S,Ito A,Arase Y,Hirose S,Tanaka Y,Suzuki H,Kagawa T |
Evidence
|
A further 14 mutations were detected in HBsAg outside the HBs antigenic determinant region: E2G, I4T, A5S, T23I, Y100C, S167L, V168A, L175S, V177A, T189I, M198T, S204N, C221Y, and Y225S.
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