|
Mutation Information
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Mutation Site
|
V124W |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
C |
Literature Information
|
PubMed PMID
|
26349829
|
|
Published Year
|
2015 |
|
Journal
|
Antimicrobial agents and chemotherapy |
|
Title
|
A novel pyridazinone derivative inhibits hepatitis B virus replication by inducing genome-free capsid formation. |
|
Author
|
Wang YJ,Lu D,Xu YB,Xing WQ,Tong XK,Wang GF,Feng CL,He PL,Yang L,Tang W,Hu YH,Zuo JP |
|
Evidence
|
A Cp V124W mutant, which strengthens capsid interdimer interactions, recapitulated the effect of 3711 on capsid assembly.
|
|
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HBV Mutation Detail Information