HIV Mutation Detail Information

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Mutation Information
Mutation Site V108I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NNRTIs
Country Cameroon
Literature Information
PubMed PMID 32843050
Disease HIV infection/AIDS
Published Year 2020
Journal Antimicrobial resistance and infection control
Title First case of Dolutegravir and Darunavir/r multi drug-resistant HIV-1 in Cameroon following exposure to Raltegravir: lessons and implications in the era of transition to Dolutegravir-based regimens.
Author Fokam J,Takou D,Semengue ENJ,Teto G,Beloumou G,Dambaya B,Santoro MM,Mossiang L,Billong SC,Cham F,Sosso SM,Temgoua ES,Nanfack AJ,Moudourou S,Kamgaing N,Kamgaing R,Ngako Pamen JN,Etame MMN,Bissek AZ,Elat JN,Moussi EE,Colizzi V,Perno CF,Ndjolo A,VIROFORUM.
Evidence Prior to ART re-initiation in 2010, genotypic resistance testing (GRT) results, interpreted throughout using Stanford HIVDB (http://www.hivdb.stanford.edu) and International AIDS Society mutations list, showed the presence of one resistance associated mutation (RAM) to NRTI (V75I), two non-NRTI RAMs (K103I, V108I).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation