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Mutation Information
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Mutation Site
|
V108I |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
IN |
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Country
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USA |
Literature Information
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PubMed PMID
|
30305383
|
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Disease
|
HIV infection/AIDS
|
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Published Year
|
2018 |
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Journal
|
Journal of clinical microbiology |
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Title
|
Limited Marginal Utility of Deep Sequencing for HIV Drug Resistance Testing in the Age of Integrase Inhibitors. |
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Author
|
Dalmat RR,Makhsous N,Pepper GG,Magaret A,Jerome KR,Wald A,Greninger AL |
|
Evidence
|
In three other Pr-RT tests, Sanger reported mutations that were detected at less than 20% allele frequency by NGS: V108I was called by HyDRA (15.9%) and PASeq (17.1%) (7.0%), and H221Y was called by HyDRA (17.9%) and PASeq (17.7%) (Fig. 3C).
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HIV Mutation Detail Information