HIV Mutation Detail Information

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Mutation Information

Mutation Site	V106M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Country	China

Literature Information

PubMed PMID	32267205
Disease	HIV infection/AIDS
Published Year	2020
Journal	Emerging microbes & infections
Title	Efficacy and safety of lower dose tenofovir disoproxil fumarate and efavirenz versus standard dose in HIV-infected, antiretroviral-naive adults: a multicentre, randomized, noninferiority trial.
Author	Chen J,Chen R,Shen Y,Wei H,Wang X,Zhang R,Hu Z,Xie R,Huang Q,Wang J,Liu L,Qi T,Wang Z,Song W,Tang Y,Sun J,Lu H
Evidence	One patient (standard dose regimen group) withdraw in week 4 due to high-level resistance to EFV (V106M mutation developed), while another nine patients had HIV-1 RNA of higher than 50 copies per mL at week 48(4 in standard and 5 in lower dose group).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation