|
Mutation Information
|
Mutation Site
|
V106M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
nevirapine (NVP) |
|
Country
|
Uganda |
Literature Information
|
PubMed PMID
|
18582198
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2008 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Nevirapine resistance in women and infants after first versus repeated use of single-dose nevirapine for prevention of HIV-1 vertical transmission. |
|
Author
|
Flys TS,McConnell MS,Matovu F,Church JD,Bagenda D,Khaki L,Bakaki P,Thigpen MC,Eure C,Fowler MG,Eshleman SH |
|
Evidence
|
One infant, who had K103N+Y181C at 6 weeks, had Y181C detected at 6 months. In two infants, the same mutation was detected at 6 weeks and 6 months (one with V106M and one with Y181C).
|
|
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HIV Mutation Detail Information