Mutation Information
Mutation Site
|
T97T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Relevant Drug
|
INSTIs |
Country
|
Finland |
Literature Information
PubMed PMID
|
28212411
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2017 |
Journal
|
PloS one |
Title
|
Lack of impact of pre-existing T97A HIV-1 integrase mutation on integrase strand transfer inhibitor resistance and treatment outcome. |
Author
|
Abram ME,Ram RR,Margot NA,Barnes TL,White KL,Callebaut C,Miller MD |
Evidence
|
The T97A (or T97T/A) integrase mutation was detected as an infrequent, naturally occurring integrase polymorphism among all available pre-treatment integrase sequences in 1.4% of patients (47 of 3367) (Table 1 and Fig 2; S1 Table and S1 Fig).
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