Mutation Information
Mutation Site
|
T8I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
CA |
Literature Information
PubMed PMID
|
33692109
|
Published Year
|
2021 |
Journal
|
Science advances |
Title
|
A stable immature lattice packages IP6 for HIV capsid maturation. |
Author
|
Mallery DL,Kleinpeter AB,Renner N,Faysal KMR,Novikova M,Kiss L,Wilson MSC,Ahsan B,Ke Z,Briggs JAG,Saiardi A,Böcking T,Freed EO,James LC |
Evidence
|
This was most notable for K158T, which was largely processed in the presence of PF96, whereas for K158T/T8I, over 50% of p25 remained unprocessed upon addition of the MI (Fig. 4D).
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