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Mutation Information
|
Mutation Site
|
T846C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E7 |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
21436703
|
|
Disease
|
Cervicitis;
Cervical intraepithelial neoplasia;
Cervical carcinoma
|
|
Published Year
|
2011 |
|
Journal
|
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society |
|
Title
|
Genetic diversity of HPV-16 E6, E7, and L1 genes in women with cervical lesions in Liaoning Province, China. |
|
Author
|
Sun Z,Ren G,Cui X,Zhou W,Liu C,Ruan Q |
|
Evidence
|
The results also showed the prevalence of 4 hot spots of E7 nucleotide variations leading to N29H, N29S, and 2 silent variations, nucleotide G666A and nucleotide T846C, with 4.2% (6/142), 43% (61/142), 32.4% (46/142), and 43% (61/142), respectively.
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HPV Mutation Detail Information