Mutation Information
Mutation Site
|
T7546C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
LCR |
Genotype/Subtype
|
HPV11 |
Viral Reference
|
M14119
|
Literature Information
PubMed PMID
|
23649705
|
Disease
|
Papilloma
|
Published Year
|
2013 |
Journal
|
Medical microbiology and immunology |
Title
|
Genomic differences in the background of different severity in juvenile-onset respiratory papillomatoses associated with human papillomavirus type 11. |
Author
|
Gáll T,Kis A,Tatár TZ,Kardos G,Gergely L,Szarka K |
Evidence
|
HPV11s in both solitary papillomas had identical LCRs containing a T7546C polymorphism, which strongly attenuated LCR activity, as confirmed by site-directed mutagenesis.
|
|
|