HPV Mutation Detail Information

> T732C Search Result


Mutation Information
Mutation Site T732C
Mutation Type Nucleotide level
Gene/Protein/Region Type E7
Genotype/Subtype HPV16
Country Korea
Literature Information
PubMed PMID 16012730
Disease Cervical carcinoma
Published Year 2005
Journal Oncology reports
Title Sequence variation and the transcriptional activity of the upstream regulatory region in human papillomavirus 16 E7 variants in cervical cancer of Korean women.
Author Kim YB,Song YS,Jeon YT,Park JS,Um SJ,Kim JW,Park NH,Kang SB,Lee HP
Evidence Using PCR-directed sequencing, the presence of sequence variations in URRs were analyzed and the sites of sequence variation were matched with the known transcriptional factor binding site (TFBS) in 26 HPV 16 E7 variants, 21 cases with A647G (KE7-1, high oncogenic potential) and 5 cases with T732C (KE7-2, low oncogenic potential).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation