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Mutation Information
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Mutation Site
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T69G |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
|
NRTIs |
Literature Information
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PubMed PMID
|
30174310
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Published Year
|
2018 |
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Journal
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Cell chemical biology |
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Title
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The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase. |
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Author
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Takamatsu Y,Das D,Kohgo S,Hayashi H,Delino NS,Sarafianos SG,Mitsuya H,Maeda K |
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Evidence
|
We previously selected an HIV-1EFdAR variant harboring M41L, D67Delta, T69G, K70R, L74I, V75T, M184V, T215F, and K219Q mutations (Figure 2A).
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HIV Mutation Detail Information