|
Mutation Information
|
Mutation Site
|
T68I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
AB033550
|
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
18939932
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2008 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Combined mutations in pre-s/surface and core promoter/precore regions of hepatitis B virus increase the risk of hepatocellular carcinoma: a case-control study. |
|
Author
|
Chen CH,Changchien CS,Lee CM,Hung CH,Hu TH,Wang JH,Wang JC,Lu SN |
|
Evidence
|
Compared with patients without pre-S deletions, patients with pre-S deletions had higher rates of HBeAg positivity; HBV genotype C, K7T/N, and T68I/V in pre-S1 genes; C75Y in surface genes; and T1762/A1764 mutations.
|
|
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HBV Mutation Detail Information