Mutation Information
Mutation Site
|
T675A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Env |
Viral Reference
|
AAB50262.1
|
Literature Information
PubMed PMID
|
31504041
|
Published Year
|
2019 |
Journal
|
PloS one |
Title
|
Identification of variant HIV envelope proteins with enhanced affinities for precursors to anti-gp41 broadly neutralizing antibodies. |
Author
|
Zhu H,Mathew E,Connelly SM,Zuber J,Sullivan M,Piepenbrink MS,Kobie JJ,Dumont ME |
Evidence
|
Effect of truncation (after W670) or mutagenesis (substitutions W672A F673A T675A) of the epitope for mature 4E10 on the binding of mature 4E10 to variant and otherwise unmutagenized forms of QH0692 gp140dsm
|
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