|
Mutation Information
|
Mutation Site
|
T64A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Tat |
|
Combined Mutation
|
tat.T68A+tat.T64A+tat.S62A |
Literature Information
|
PubMed PMID
|
15737233
|
|
Published Year
|
2005 |
|
Journal
|
Virology journal |
|
Title
|
Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription. |
|
Author
|
Endo-Munoz L,Warby T,Harrich D,McMillan NA |
|
Evidence
|
However, the percentage of phosphorylation at 15 minutes for the other double mutants and for the triple mutant decreased to 68% for Tat T64A.S68A, 48% for Tat S62A.S68A, and 56% for Tat S62A.T64A.S68A.
|
|
|
HIV Mutation Detail Information