Mutation Information
Mutation Site
|
T569A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gp41 |
Viral Reference
|
AF407156
|
Country
|
Kenya |
Literature Information
PubMed PMID
|
18177204
|
Published Year
|
2008 |
Journal
|
PLoS medicine |
Title
|
Enhancing exposure of HIV-1 neutralization epitopes through mutations in gp41. |
Author
|
Blish CA,Nguyen MA,Overbaugh J |
Evidence
|
The first mutation, T569A, involved the substitution of a conserved threonine (T) to an alanine (A) within heptad repeat 1 (HR1) of gp41;this mutation is referred to subsequently as TA (Figure 1A).
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