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Mutation Information
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Mutation Site
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T54A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
CA |
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Viral Reference
|
K02013.1
|
Literature Information
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PubMed PMID
|
24415937
|
|
Published Year
|
2014 |
|
Journal
|
PLoS pathogens |
|
Title
|
In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects. |
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Author
|
Henning MS,Dubose BN,Burse MJ,Aiken C,Yamashita M |
|
Evidence
|
The T54A mutant is defective even in proliferating cells; however, as one of the cell cycle-dependent CA mutants, its infection is more severely impaired in non-dividing cells.
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HIV Mutation Detail Information