Mutation Information
Mutation Site
|
T540C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
S |
Nucleotide_Mutation
|
Q129R |
Literature Information
PubMed PMID
|
9303514
|
Clinical information
|
Yes
|
Disease
|
Fulminant hepatitis B;
Acute hepatitis B
|
Published Year
|
1997 |
Journal
|
Hepatology (Baltimore, Md.) |
Title
|
Surface gene mutants of hepatitis B virus in infants who develop acute or chronic infections despite immunoprophylaxis. |
Author
|
Hsu HY,Chang MH,Ni YH,Lin HH,Wang SM,Chen DS |
Evidence
|
patient 8 (C) had S mutant with T-to-C mutation at nucleotide position 540 , leading to amino acid change from glycine to arginine at residue 129
|
|
|