Mutation Information
Mutation Site
|
T53C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreS2 |
Country
|
China |
Literature Information
PubMed PMID
|
24849936
|
Disease
|
Hepatocellular carcinoma
|
Published Year
|
2014 |
Journal
|
PloS one |
Title
|
Association of hepatitis B virus pre-S deletions with the development of hepatocellular carcinoma in Qidong, China. |
Author
|
Qu LS,Liu JX,Liu TT,Shen XZ,Chen TY,Ni ZP,Lu CH |
Evidence
|
RESULTS: After adjustment for age, history of cigarette smoking and alcohol consumption, HBeAg positivity, pre-S deletions, pre-S2 start codon mutations, and T53C mutation were significantly associated with HCC, showing adjusted odds ratios (ORs) from 1.
|
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