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Mutation Information
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Mutation Site
|
T53C |
|
Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
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PreS |
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Country
|
China |
Literature Information
|
PubMed PMID
|
20160279
|
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Disease
|
Hepatocellular carcinoma
|
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Published Year
|
2010 |
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Journal
|
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology |
|
Title
|
Distribution and hepatocellular carcinoma-related viral properties of hepatitis B virus genotypes in Mainland China: a community-based study. |
|
Author
|
Yin J,Zhang H,He Y,Xie J,Liu S,Chang W,Tan X,Gu C,Lu W,Wang H,Bi S,Cui F,Liang X,Schaefer S,Cao G |
|
Evidence
|
After sequencing the PreS region from 522 samples and the EnhII/BCP/Precore region from 750 samples, we rated the HCC-associated HBV mutations including PreS deletion, T31C, T53C, C1653T, T1753V, A1762T/G1764A, and G1899 A (20-31); fulminant hepatitis B–associated mutation G1896A (40); and liver cirrhosis–associated mutations C1766T (20).
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HBV Mutation Detail Information