|
Mutation Information
|
Mutation Site
|
T484G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
S |
|
Nucleotide_Mutation
|
I110M |
|
Genotype/Subtype
|
A |
|
Country
|
France |
Literature Information
|
PubMed PMID
|
15016847
|
|
Disease
|
HBV infection
|
|
Published Year
|
2004 |
|
Journal
|
Journal of virology |
|
Title
|
Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene. |
|
Author
|
Khan N,Guarnieri M,Ahn SH,Li J,Zhou Y,Bang G,Kim KH,Wands JR,Tong S |
|
Evidence
|
Surprisingly, a T484G mutation in the 4B genome, generating an I110M substitution in the S domain, could also reduce HBsAg secretion and block virion secretion.
|
|
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HBV Mutation Detail Information