Mutation Information
Mutation Site
|
T458S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
E1 |
Amino acid_Mutation
|
C2237G |
Genotype/Subtype
|
HPV16 |
Viral Reference
|
K02718.1
|
Country
|
China |
Literature Information
PubMed PMID
|
31341418
|
Disease
|
Cervical carcinoma
|
Published Year
|
2019 |
Journal
|
International journal of medical sciences |
Title
|
Human Papillomavirus Type 16 E1 Mutations Associated with Cervical Cancer in a Han Chinese Population. |
Author
|
Yao Y,Yan Z,Dai S,Li C,Yang L,Liu S,Zhang X,Shi L,Yao Y |
Evidence
|
Moreover, the T921C (T19T), T933A (A23A), T1014G (D50E), A1041G (L59L), C1096G (Q78E), G1163A (G100E), T1200C (A112A), T1366A (C168S), T1407G (S181R), C1426G (Q188E), T1486C (L208L), T1522A (S220T), C1624T (L154L), A1668G (A268A), C1744A (L294M), C2041T (L393L), G2220C (E452D), T2232C (F456F), C2237G (T458S), G2249A (R462K), C2262T (G466G), C2287T (L475L), T2567G (I568S), T2586C (S574S), A2608C (R582R), T2631A (P589P) and G2650A (E596K) mutations were found only in the case group. In the control group, 171 HPV16-positive asymptomatic individuals were accepted into this study.
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