Mutation Information
Mutation Site
|
T301P |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
L1 |
Genotype/Subtype
|
HPV16 |
Literature Information
PubMed PMID
|
28968823
|
Published Year
|
2017 |
Journal
|
The Journal of infectious diseases |
Title
|
Naturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization. |
Author
|
Ning T,Wolfe A,Nie J,Huang W,Chen XS,Wang Y |
Evidence
|
Nine single mutants with a frequency of ≥0.81% among the 142 Chinese sequences but <1.0% among the 1204 global sequences were selected, including T301P (mutation frequency, 5.65%), D202H (3.23%), E352K (3.23%), K467R (2.42%), G483R (2.42%), A9Y (1.61%), K361E (1.61%), S302L (0.81%), and S302P (0.81%).
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