Mutation Information
Mutation Site
|
T298A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
BXLF1 |
Literature Information
PubMed PMID
|
15779905
|
Published Year
|
2005 |
Journal
|
Biochemistry |
Title
|
Characterization of three essential residues in the conserved ATP-binding region of Epstein-Barr virus thymidine kinase. |
Author
|
Wu CC,Hsu TY,Chen JY |
Evidence
|
While EBV TK mutant T298S retained approximately 80% of wtTK enzyme activity, T298A lost its enzyme activity, suggesting that a hydroxyl group at this position is important for the enzyme activity.
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