HIV Mutation Detail Information

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Mutation Information

Mutation Site	T280S
Mutation Type	Amino acid level
Gene/Protein/Region Type	Gag
Viral Reference	K03455.1
Country	Brazil

Literature Information

PubMed PMID	30201008
Clinical information	Yes
Disease	HIV infection/AIDS
Published Year	2018
Journal	Retrovirology
Title	Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control.
Author	Caetano DG,Côrtes FH,Bello G,Teixeira SLM,Hoagland B,Grinsztejn B,Veloso VG,Guimarães ML,Morgado MG
Evidence	For EC18, Nef epitope mutation K92R appeared only at VL (68%);for Gag, epitope mutations K28R, I34L, R39 K and T280S became the majority at VL, whereas R43Q and R76K mutations decreased from VE (approximately 20%) to undetectable levels at VL.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation