Mutation Information
Mutation Site
|
T26S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Literature Information
PubMed PMID
|
18163907
|
Published Year
|
2007 |
Journal
|
Retrovirology |
Title
|
Design of a trans protease lentiviral packaging system that produces high titer virus. |
Author
|
Westerman KA,Ao Z,Cohen EA,Leboulch P |
Evidence
|
We also replaced wt PR with a slightly less active T26S PR mutant in an effort to prevent premature processing and cytoxicity associated with wt PR.
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