Mutation Information
Mutation Site
|
T242N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gag |
Country
|
Durban; South Africa |
Literature Information
PubMed PMID
|
18369479
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2008 |
Journal
|
PLoS pathogens |
Title
|
Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage. |
Author
|
Chopera DR,Woodman Z,Mlisana K,Mlotshwa M,Martin DP,Seoighe C,Treurnicht F,de Rosa DA,Hide W,Karim SA,Gray CM,Williamson C,CAPRISA 002 Study Team. |
Evidence
|
Nine of the 21 study participants were infected with viruses carrying the A146X (X = P, or S) polymorphism and the viruses in six of these nine individuals also carried the T242N mutation.
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