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Mutation Information
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Mutation Site
|
T2254C |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
|
E1 |
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Nucleotide_Mutation
|
L464L |
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Genotype/Subtype
|
HPV16 |
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Viral Reference
|
K02718.1
|
|
Country
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China |
Literature Information
|
PubMed PMID
|
31341418
|
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Disease
|
Cervical carcinoma
|
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Published Year
|
2019 |
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Journal
|
International journal of medical sciences |
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Title
|
Human Papillomavirus Type 16 E1 Mutations Associated with Cervical Cancer in a Han Chinese Population. |
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Author
|
Yao Y,Yan Z,Dai S,Li C,Yang L,Liu S,Zhang X,Shi L,Yao Y |
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Evidence
|
For the D3 (AA1) sub-lineage, which occurred only in the case group, a total of twenty-eight mutations with a frequency of 100% were found; except for T1139G (V92G), C1377T (Y171Y), A1842G (I326M), T2254C (L464L), T2343C (F493F) and C2344T (L494L), these mutations occurred only in the D3 (AA1) sub-lineage. Of these mutations, twelve were non-synonymous (Table (Table33).
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HPV Mutation Detail Information