|
Mutation Information
|
Mutation Site
|
T218I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
INSTIs |
|
Country
|
South Africa;Cameroon |
Literature Information
|
PubMed PMID
|
32858802
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Structural Comparison of Diverse HIV-1 Subtypes using Molecular Modelling and Docking Analyses of Integrase Inhibitors. |
|
Author
|
Isaacs D,Mikasi SG,Obasa AE,Ikomey GM,Shityakov S,Cloete R,Jacobs GB |
|
Evidence
|
The alignment also showed 17 NOPs within a South African cohort-derived Subtype C consensus sequence, namely D25E, V31I, M50I, V72I, F100Y, L101I, T112V, T124A, T125A, K136Q, I151V, V201I, T218I, V234I, R269K, D278A, S283G (Supplementary Figure S1).
|
|
|
HIV Mutation Detail Information