Mutation Information
Mutation Site
|
T218I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Country
|
Cameroon |
Literature Information
PubMed PMID
|
32106437
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
International journal of molecular sciences |
Title
|
Variability in HIV-1 Integrase Gene and 3'-Polypurine Tract Sequences in Cameroon Clinical Isolates, and Implications for Integrase Inhibitors Efficacy. |
Author
|
Acharya A,Tagny CT,Mbanya D,Fonsah JY,Nchindap E,Kenmogne L,Jihyun M,Njamnshi AK,Kanmogne GD |
Evidence
|
Integrase polymorphisms in database samples: The L101I, T125A, G134N, I135V, K136T, T206S, T218I, and R269K polymorphisms were present in a significantly higher proportion of AG (44% to 95%) compared to non-AG (5-66%) database samples (p < 0.00002, Table 5).
|
|
|