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Mutation Information
Mutation Site T218I
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Country Cameroon
Literature Information
PubMed PMID 32106437
Disease HIV infection/AIDS
Published Year 2020
Journal International journal of molecular sciences
Title Variability in HIV-1 Integrase Gene and 3'-Polypurine Tract Sequences in Cameroon Clinical Isolates, and Implications for Integrase Inhibitors Efficacy.
Author Acharya A,Tagny CT,Mbanya D,Fonsah JY,Nchindap E,Kenmogne L,Jihyun M,Njamnshi AK,Kanmogne GD
Evidence Integrase polymorphisms in database samples: The L101I, T125A, G134N, I135V, K136T, T206S, T218I, and R269K polymorphisms were present in a significantly higher proportion of AG (44% to 95%) compared to non-AG (5-66%) database samples (p < 0.00002, Table 5).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation