HIV Mutation Detail Information

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Mutation Information

Mutation Site	T215Y
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NRTIs
Country	America

Literature Information

PubMed PMID	29846534
Disease	HIV infection/AIDS
Published Year	2019
Journal	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Title	Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted Human Immunodeficiency Virus Type 1 Drug Resistance in a Large US Clinic Population.
Author	Rhee SY,Clutter D,Fessel WJ,Klein D,Slome S,Pinsky BA,Marcus JL,Hurley L,Silverberg MJ,Kosakovsky Pond SL,Shafer RW
Evidence	Although the spectrum of NRTI-associated SDRMs was diverse, >80% of NRTI TDR cases were caused by TAMs, of which those other than T215Y/F may have little impact on currently used NRTIs.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation