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Mutation Information
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Mutation Site
|
T215Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.L210W+rt.T215Y+rt.M41L;rt.T215Y+rt.M41L |
|
Viral Reference
|
K03455.1
|
|
Country
|
Panama |
Literature Information
|
PubMed PMID
|
27119150
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2016 |
|
Journal
|
PloS one |
|
Title
|
HIV-1 Antiretroviral Drug Resistance Mutations in Treatment Naïve and Experienced Panamanian Subjects: Impact on National Use of EFV-Based Schemes. |
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Author
|
Mendoza Y,Castillo Mewa J,Martínez AA,Zaldívar Y,Sosa N,Arteaga G,Armién B,Bautista CT,García-Morales C,Tapia-Trejo D,Ávila-Ríos S,Reyes-Terán G,Bello G,Pascale JM |
|
Evidence
|
Of the 467 ARV drug-experienced and of the 250 ARV drug-naïve subjects, 167 and 10 subjects harbored tymidine-analog-mutations (TAMs), respectively. In ARV drug-experienced subjects, TAMs found were T215Y/F (26.8%), K70R (15.2%), M41L (13.7%), K219E/Q (12.2%), D67N (10.9%), and L210W (7.5%) (Fig 1A).
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HIV Mutation Detail Information