|
Mutation Information
|
Mutation Site
|
T215Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
thymidineanalogue (TAMs) |
Literature Information
|
PubMed PMID
|
16524459
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2006 |
|
Journal
|
BMC infectious diseases |
|
Title
|
DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes. |
|
Author
|
Garriga C,Menéndez-Arias L |
|
Evidence
|
However, mutational patterns conferring resistance to zalcitabine, didanosine, stavudine and abacavir are complex, and the contribution of thymidine analogue resistance mutations (M41L, D67N, K70R, L210W, T215F/Y, K219Q/E) is poorly-defined in vivo, particularly when other mutations such as L74V or M184V are present.
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|
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HIV Mutation Detail Information