Mutation Information
Mutation Site
|
T215N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
abacavir (ABC);zidovudine (AZT);stavudine (D4T);didanosine (DDI);emtricitabine (FTC);emtricitabine (FTC);lamivudine (LAM);tenofovir (TDF);efavirenz (EFV);etravirine(ETR);nevirapine (NPV);rilpivirine (RPV) |
Country
|
India |
Literature Information
PubMed PMID
|
30315192
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2018 |
Journal
|
Scientific reports |
Title
|
Antiretroviral resistance, genotypic characterization and origin of Human Immunodeficiency Virus among the infected wives of Intravenous drug users in Manipur. |
Author
|
Sharma AL,Singh TR,Singh LS |
Evidence
|
NRTI positions: M184V (10%, 3/30), M184I (6.7%, 2/30) and M41L, D67N, T69D, K70G/R, Y115F, T215N and K219R/Q (3.3% each, 1/30) (ii) NNRTI positions: A98G, K103N, V179D/E, Y181C, G190A/R (6.7% each, 2/30), K101E, V106A/M, V108I, Y181F, H221Y and M230I (3.3% each, 1/30) and (iii) protease inhibitors positions: major mutation M46L (3.3%, 1/30) and other mutations L24I, G48K and G73S (3.3% each, 1/30).
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