HIV Mutation Detail Information

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Mutation Information

Mutation Site	T215I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Viral Reference	K03455.1
Country	North Carolina

Literature Information

PubMed PMID	32663847
Disease	HIV infection/AIDS
Published Year	2021
Journal	The Journal of infectious diseases
Title	Near Real-Time Identification of Recent Human Immunodeficiency Virus Transmissions, Transmitted Drug Resistance Mutations, and Transmission Networks by Multiplexed Primer ID-Next-Generation Sequencing in North Carolina.
Author	Zhou S,Sizemore S,Moeser M,Zimmerman S,Samoff E,Mobley V,Frost S,Cressman A,Clark M,Skelly T,Kelkar H,Veluvolu U,Jones C,Eron J,Cohen M,Nelson JAE,Swanstrom R,Dennis AM
Evidence	In contrast, the prevalence of PR region mutations M46L/I, D30N, V82A, and RT region mutations M41L, D67N, G190E, T215F/I/C/ D/V/E increased greatly (up to 10-fold), with an increase in detection sensitivity from 30% to 0.3%.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation