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Mutation Information
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Mutation Site
|
T215I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B;CRF01_AE;CRF07_BC;CRF08_BC |
|
Relevant Drug
|
NRTIs |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
31922125
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
EClinicalMedicine |
|
Title
|
Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001-2017). |
|
Author
|
Zuo L,Liu K,Liu H,Hu Y,Zhang Z,Qin J,Xu Q,Peng K,Jin X,Wang JH,Zhang C |
|
Evidence
|
The top NRTI mutations identified in ART-naive and ART-treated individuals were M184V/I (16.3% and 41.8%) and T215I/Y/S/D/F (20.9% and 9.5%), and the top NNRTI mutations were K103N/S (18.7% and 40.5%), Y181C/I (14.0% and 22.2%), and G190A/S (9.5% and 22.2%, respectively).
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HIV Mutation Detail Information