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Mutation Information
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Mutation Site
|
T215F |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NRTIs |
|
Country
|
Portugal |
Literature Information
|
PubMed PMID
|
32121161
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
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Journal
|
Viruses |
|
Title
|
Molecular Epidemiology of HIV-1 Infected Migrants Followed up in Portugal: Trends between 2001-2017. |
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Author
|
Pimentel V,Pingarilho M,Alves D,Diogo I,Fernandes S,Miranda M,Pineda-Pena AC,Libin P,Martins MRO,Vandamme AM,Camacho R,Gomes P,Abecasis A |
|
Evidence
|
Overall, among the 144 DN patients with TDR to NRTI (14,2%;95% CI: 12.1%-16.4%), associated with low to high resistance to a drug according to the Stanford HIV database algorithm v 8.4, the most prevalent mutations (>=10% of individuals harboring mutations) were M184V (n = 24;25%), M41L (n = 14;15%), T215F/Y/S (n = 12;13%).
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HIV Mutation Detail Information