HIV Mutation Detail Information

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Mutation Information
Mutation Site T215F
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug zidovudine (AZT);tenofovir (TDF)
Country Cameroon
Literature Information
PubMed PMID 30871487
Disease HIV infection/AIDS
Published Year 2019
Journal BMC infectious diseases
Title HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical practice in Cameroon.
Author Takou D,Fokam J,Teto G,Santoro MM,Ceccherini-Silberstein F,Nanfack AJ,Sosso SM,Dambaya B,Salpini R,Billong SC,Gori C,Fokunang CN,Cappelli G,Colizzi V,Perno CF,Ndjolo A
Evidence Thymidine-analogue mutations (TAMs)-1 [T215FY (46.53%), M41 L (22.77%), L210 W (8.91%)], with cross-resistance to AZT and TDF, were higher compared to TAMs-2 [D67N (21.78%), K70R (19.80%), K219QE (18.81%)].

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation