Mutation Information
Mutation Site
|
T215F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
abacavir (ABC);zidovudine (AZT);stavudine (D4T);didanosine (DDI);emtricitabine (FTC);emtricitabine (FTC);lamivudine (LAM);efavirenz (EFV);etravirine(ETR);nevirapine (NPV);rilpivirine (RPV) |
Country
|
India |
Literature Information
PubMed PMID
|
30315192
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2018 |
Journal
|
Scientific reports |
Title
|
Antiretroviral resistance, genotypic characterization and origin of Human Immunodeficiency Virus among the infected wives of Intravenous drug users in Manipur. |
Author
|
Sharma AL,Singh TR,Singh LS |
Evidence
|
The common DRMs found among the ART naive patients were targeted at (i) NRTI positions: M184V (21.4%, 3/14), K219Q (14.2%, 2/14) and K65R, Y115F and T215F (7.1% each, 1/14) (ii) NNRTI positions: Y181C (14.2%, 2/14) and K103N, G190A and Y188L (7.1% each, 1/14) and (iii) protease inhibitors positions: I54V, L76V and I84V (7.1% each,1/14).
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