HIV Mutation Detail Information

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Mutation Information

Mutation Site	T215F
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	B
Viral Reference	K03455.1
Country	USA

Literature Information

PubMed PMID	18271957
Disease	HIV infection/AIDS
Published Year	2008
Journal	Retrovirology
Title	Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase.
Author	Huigen MC,van Ham PM,de Graaf L,Kagan RM,Boucher CA,Nijhuis M
Evidence	Multiple studies have identified mutations at (at least) six codons in the reverse transcriptase (RT) enzyme (thymidine analogue associated mutations (TAMs);M41L, D67N, K70R, L210W, T215Y/F and K219Q/E) that can cause a decrease in Zidovudine susceptibility.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation