HIV Mutation Detail Information

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Mutation Information
Mutation Site T215F
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype B
Viral Reference K03455.1
Country USA
Literature Information
PubMed PMID 18271957
Disease HIV infection/AIDS
Published Year 2008
Journal Retrovirology
Title Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase.
Author Huigen MC,van Ham PM,de Graaf L,Kagan RM,Boucher CA,Nijhuis M
Evidence Multiple studies have identified mutations at (at least) six codons in the reverse transcriptase (RT) enzyme (thymidine analogue associated mutations (TAMs);M41L, D67N, K70R, L210W, T215Y/F and K219Q/E) that can cause a decrease in Zidovudine susceptibility.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation