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Mutation Information
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Mutation Site
|
T215C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NRTIs |
|
Country
|
Mexico |
Literature Information
|
PubMed PMID
|
31819984
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Pretreatment HIV drug resistance spread within transmission clusters in Mexico City. |
|
Author
|
Matías-Florentino M,Chaillon A,Ávila-Ríos S,Mehta SR,Paz-Juárez HE,Becerril-Rodríguez MA,Del Arenal-Sánchez SJ,Piñeirúa-Menéndez A,Ruiz V,Iracheta-Hernández P,Macías-González I,Tena-Sánchez J,Badial-Hernández F,González-Rodríguez A,Reyes-Terán G |
|
Evidence
|
Other frequently shared DRMs included: reverse transcriptase (RT) Y188L (11/175), RT T215S/C (24/175) and protease M46I (19/175), mostly at >=20% within-host frequency;and RT D67N/G/E (56/175) and RT P225H (16/175) as low-frequency variants.
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HIV Mutation Detail Information