|
Mutation Information
|
Mutation Site
|
T215C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NRTIs |
|
Country
|
Canada |
Literature Information
|
PubMed PMID
|
19005274
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2008 |
|
Journal
|
AIDS (London, England) |
|
Title
|
Transmission networks of drug resistance acquired in primary/early stage HIV infection. |
|
Author
|
Brenner BG,Roger M,Moisi DD,Oliveira M,Hardy I,Turgel R,Charest H,Routy JP,Wainberg MA,Montreal PHI Cohort and HIV Prevention Study Groups. |
|
Evidence
|
The transmission of nucleoside analogue mutations and 215 resistant variants (T215C/D/I/F/N/S/Y) declined with clustering (7.9% vs. 3.4% vs. 1.2% and 5.8% vs. 1.7% vs. 1.1% for unique, small and large clustered transmissions, respectively).
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HIV Mutation Detail Information